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This Pharma Company Is Preparing To Launch Its Lead Candidate

Benzinga

By Johnny Rice, Benzinga Leonard Mazur, CEO and founder of Citius Pharmaceuticals (NASDAQ: CTXR), was recently interviewed by Benzinga. Citius Pharmaceuticals, Inc. is a late-stage biopharmaceutical company focused on the development and commercialization of first-in-class critical care products, with a pipeline of anti-infectives in adjunct cancer care, stem cell therapy, and unique prescription products. Mazur spoke about the exciting developments in the company’s assets, including the imminent launch of its first drug on the market. Learn more here: Featured photo by freestocks on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

July 25, 2024 08:58 AM Eastern Daylight Time

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Heat Stroke and Heat-Related Illness Rapidly Rising as Global Temperatures Climb

Centre for Neuro Skills

The number of people exposed to extreme heat has grown exponentially due to climate change, according to the World Health Organization. The New York Times reported that June 2024 was the 13 th consecutive month to break the global heat record. In 2023, 32 million people across California, Texas and Nevada experienced the hottest summer ever recorded in the United States. Centre for Neuro Skills (CNS), a leading provider of traumatic and acquired brain injury rehabilitation services with seven locations in California and Texas, shares essential tips for heat stroke prevention. Taking proactive measures to avoid heat stroke can be the difference between life and death. To avoid heat stroke: Dress in lightweight, loose-fitting clothing Apply sunscreen to avoid sunburn and keep the body cool Drink plenty of water and avoid sugary or alcoholic drinks Limit time outside to when it is cooler or if you must go out when temperatures are high, rest often Avoid leaving children or animals in parked cars, even if the windows are cracked open Monitor loved ones who are at high risk for developing heat stroke Check local news for extreme heat alerts “Of all the heat-related illnesses, heat stroke is the most serious. Heat stroke occurs when the body is no longer able to regulate temperature and cool down,” said Dr. Gary Seale, Regional Director of Clinical Services at CNS. “Body temperatures can rise rapidly to 104 degrees or higher which can cause damage to organs, including the brain, and result in permanent disability. Heat stroke can cause brain swelling, seizures, and lead to chronic inflammation, all of which disrupt brain function.” Children under 4 years old, adults over 65 years old with illnesses or medications that prevent body temperature regulation and people that are clinically classified as obese are all at higher risk of heat stroke. Heat exhaustion can be caused by engaging in strenuous activity, overexposure to hot weather and humidity and wearing excessive clothing that does not allow sweat to evaporate. Symptoms of heat stroke include high body core temperature, flushed skin, dizziness, loss of consciousness for longer than a few seconds, rapid heart rate, difficulty breathing, muscle cramps, seizures, vomiting and diarrhea. If you or a loved one are showing signs of heat stroke, call 911 immediately or transport the person to the hospital. While waiting for help, keep the person in a cool environment, remove unnecessary clothing and apply ice packs or cool water to their skin. ### About Centre for Neuro Skills Centre for Neuro Skills (CNS) is an experienced and respected world leader that provides intensive rehabilitation and medical programs for those recovering from all types of brain injury. CNS covers a full spectrum of advanced acquired and traumatic brain injury rehabilitation care, from residential and assisted living programs to outpatient rehabilitation, day treatment and telehealth services. Founded by Dr. Mark Ashley in 1980, CNS has seven locations in California and Texas and has been recognized by the American Stroke Association for its work in stroke rehabilitation. For more information about Centre for Neuro Skills, visit: www.neuroskills.com, Instagram, Facebook, X (formerly known as Twitter), LinkedIn, and YouTube. Media, please note: To request an interview with CNS leadership or clinical staff, please contact Robin Carr at 415.766.0927 or CNS@landispr.com. Contact Details Landis Communications Inc. Robin Carr +1 415-766-0927 cns@landispr.com Company Website https://www.neuroskills.com/

July 23, 2024 08:01 AM Pacific Daylight Time

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Classiq Transforms Quantum Computing with Qmod, The First High-Level Language for Quantum Programming

Classiq Technologies

Classiq today announced the general availability of Qmod (Quantum Modeling Language), the first high-level language (HLL) for quantum coding. Following successful pilot projects with enterprise partners, Qmod is now accessible to developers, researchers and enterprises worldwide and will transform quantum computing with its efficient, approachable method of programming. Qmod facilitates advanced quantum modeling and enables developers to describe quantum algorithms at a high level of abstraction. It supports unique quantum-computing concepts alongside conventional constructs found in high-level classical programming languages. This innovative approach allows developers to focus on the functional intent of their algorithms while Classiq’s powerful compiler and synthesis engine handle the intricate hardware-aware quantum implementation details. “To deliver a business or scientific value, quantum computing must be useful and accessible to scientists and engineers seeking to use quantum computing to solve real-world problems, which today it is not,” said Heather West, PhD, Research Manager, Quantum Computing at IDC. “Today, programming a quantum computer happens at the hardware level, making the technology only accessible to quantum physicists and other quantum specialists. As we begin to talk about quantum utility and near-term applications, abstraction-level application programming will become a necessity for wide-spread quantum adoption and usage.” Why The Qmod Language Is Different Declarative programming: Qmod’s declarative nature lets users define what their algorithm should achieve rather than how to achieve it; Classiq’s synthesis engine compiler optimizes for hardware and other constraints automatically. Flexibility and interoperability: Whether through native syntax, Python or graphical representation, Qmod descriptions are easily translatable and compatible across different formats and hardware. Industry-ready: Qmod is a tool for researchers and industry applications, providing robust scalable solutions for enterprise-grade quantum software development in an era of steadily growing qubit counts and the resulting coding complexity. “As we go further in building a complete quantum software stack, our groundbreaking Qmod language enables quantum experts to produce sophisticated programs while also allowing developers without a quantum background to innovate and solve complex problems across a variety of industry domains,” said Nir Minerbi, CEO and co-founder of Classiq. “By abstracting the complexities of quantum programming, Qmod delivers the ability to create and deploy dynamic quantum applications effortlessly. In some cases, it’ll use perhaps five lines of code instead of the traditional 100 lines of code. Like Java for the worldwide web or BASIC for PCs, Qmod is intended to open the gates to advanced quantum implementation.” Classiq’s platform ensures that quantum algorithms designed with Qmod can be seamlessly compiled for a broad range of hardware and simulation environments, as well as supporting seamless HPC integration. The platform's synthesis engine dynamically adapts implementations to different hardware configurations, allowing for rapid benchmarking and ensuring optimal implementations that make the very most of the available hardware. About Classiq Classiq Technologies, the leading quantum software company, provides an all-encompassing platform (IDE, compiler and OS) with a single point of entry into quantum computing, taking you from algorithm design to execution. The high-level descriptive quantum software development environment, tailored to all levels of developer proficiency, automates quantum programming. This ensures that a broad range of talents, including those with backgrounds in AI, ML and linear algebra, can harness quantum computing without requiring deep, specialized knowledge of quantum physics. Classiq democratizes access to quantum computing and equips its users to take full advantage of the quantum computing revolution, including access to a broad range of quantum hardware. Classiq’s core technology, algorithmic quantum circuit compilation, is engineered to power the quantum ecosystem of today and the future. Classiq works closely with quantum cloud providers and advanced computation hardware developers providing software for use with quantum computers, HPC, and quantum simulators. Backed by investors such as HPE, HSBC, Samsung, Intesa Sanpaolo and NTT, Classiq’s world-class team of scientists and engineers has distilled decades of quantum expertise into its groundbreaking quantum engine. Follow Classiq on LinkedIn, X (formerly Twitter) or YouTube, and visit the Slack community and https://www.classiq.io to learn more. Contact Details Rainier Communications Michelle Allard McMahon classiqPR@rainierco.com Company Website http://www.classiq.io/

July 23, 2024 08:00 AM Eastern Daylight Time

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Classiq and QuEra Announce Integration of Neutral-Atom Quantum Computers into Classiq Platform

Classiq Technologies

Classiq, the leader in quantum software development, and QuEra Computing, the leader in neutral-atom quantum computing, today announced a strategic collaboration to integrate QuEra’s cutting-edge neutral-atom quantum computers into the Classiq platform. This integration will enable customers to optimize a wide variety of quantum and hybrid quantum/classical algorithms for QuEra’s quantum computers, leveraging the unique capabilities of QuEra’s advanced quantum technology. With this collaboration, Classiq users will be able to exploit the distinctive features of QuEra’s neutral-atom quantum computers, such as the ability to simultaneously operate on multiple qubits and advanced qubit shuttling. Additionally, the integration provides access to Classiq’s extensive pre-written algorithmic blocks and allows customers to estimate the resources needed to run their algorithms. These capabilities enable the creation of highly resource-efficient algorithms with a large number of qubits and, in the future, for logical qubits as well. “Our partnership with QuEra represents a significant step forward in the quantum computing landscape,” said Nir Minerbi, CEO of Classiq. “By integrating QuEra’s neutral-atom technology into our platform, we are providing our users with unprecedented opportunities to enhance and optimize their quantum algorithms. This collaboration underscores our commitment to delivering the most versatile and powerful quantum computing solutions available.” “We are thrilled to collaborate with Classiq and bring the power of our neutral-atom quantum computers to a broader audience,” said Yuval Boger, Chief Commercial Officer of QuEra. “Classiq’s platform is renowned for its ease of use and flexibility, and by integrating our technology, we can help users unlock new potential and achieve groundbreaking results in their quantum computing projects.” The integration of QuEra’s quantum computers into the Classiq platform is expected to accelerate the development and deployment of quantum applications across various fields, including pharmaceuticals, finance, logistics and more. Customers who have purchased on-premises computers will be able to use the Classiq platform for the rapid development of quantum algorithms. This partnership highlights the ongoing commitment of both companies to drive innovation and make quantum computing more accessible and impactful. About Classiq Classiq Technologies, the leading quantum software company, provides an all-encompassing platform (IDE, compiler and OS) with a single point of entry into quantum computing, taking you from algorithm design to execution. The high-level descriptive quantum software development environment, tailored to all levels of developer proficiency, automates quantum programming. This ensures that a broad range of talents, including those with backgrounds in AI, ML and linear algebra, can harness quantum computing without requiring deep, specialized knowledge of quantum physics. Classiq democratizes access to quantum computing and equips its users to take full advantage of the quantum computing revolution, including access to a broad range of quantum hardware. Classiq’s core technology, algorithmic quantum circuit compilation, is engineered to power the quantum ecosystem of today and the future. Classiq works closely with quantum cloud providers and advanced computation hardware developers providing software for use with quantum computers, HPC, and quantum simulators. Backed by investors such as HPE, HSBC, Samsung, Intesa Sanpaolo and NTT, Classiq’s world-class team of scientists and engineers has distilled decades of quantum expertise into its groundbreaking quantum engine. Follow Classiq on LinkedIn, X (formerly Twitter) or YouTube, and visit the Slack community and https://www.classiq.io to learn more. About QuEra QuEra Computing is the leader in commercializing quantum computers using neutral atoms—widely recognized as a highly promising quantum modality. Based in Boston and built on pioneering research from nearby Harvard University and MIT, QuEra operates the world’s largest publicly accessible quantum computer, available over a major public cloud and for on-premises delivery. QuEra is developing large-scale, fault-tolerant quantum computers to tackle classically intractable problems, becoming the partner of choice in the quantum field. Simply put, QuEra is the best way to quantum. For more information, visit us at quera.com and follow us on X or LinkedIn. Contact Details Rainier Communications on behalf of Classiq Michelle Allard McMahon classiqPR@rainierco.com Merrill Freund on behalf of QuEra +1 415-577-8637 press@quera.com Company Website http://www.classiq.io/

July 23, 2024 08:00 AM Eastern Daylight Time

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Top 4 Cannabis Stocks to Watch Ahead of Potential Federal Policy Changes

RazorPitch KDLY, TLRY, CGC, ACB

When it comes to investing in the legal marijuana industry, they don't call it the "green rush" for nothing. Many analysts are projecting massive growth for the cannabis industry. New Frontier, a Washington D.C.-based cannabis research firm, expects total U.S. legal cannabis sales to exceed $57 billion by 2030. In light of such tremendous growth potential, many see marijuana as a golden investment opportunity. Cannabis is now legal in 37 states for medical use and fully legal in 23 states. However, on a federal level, its status has barely changed since the 1970s, sharing the same classification as heroin, ecstasy, and LSD. Cannabis stocks jumped after the U.S. Department of Health and Human Services recommended easing restrictions on marijuana in August. With that date approaching, let's take a look at a few stocks in the sector for your radar. KindlyMD, Inc. (NASDAQ: KDLY) is a healthcare company focused on integrating traditional primary care and pain management with behavioral and alternative therapies to combat opioid dependency in the U.S. As Utah's largest alternative pain treatment center, KindlyMD prioritizes holistic pain management and often recommends medical cannabis to improve patient health outcomes. In response to the ongoing opioid crisis, which saw over 80,000 opioid-related deaths in 2021, KindlyMD offers comprehensive care plans to ensure the safe use of opioids when necessary, including appropriate dosing and weaning plans. The company also educates patients on medical cannabis as an alternative treatment option, having conducted over 60,000 patient visits to date. Last month, KindlyMD successfully completed its initial public offering, raising approximately $6.8 million. This milestone demonstrates strong investor confidence in the company's comprehensive approach to healthcare. KDLY announced in June that it had become the first alternative medical treatment company in Utah to sign contracts with the state's top insurance payors, including Select Health, Medicare, and Medicaid. This credentialing allows nearly 70% of Utah's population to access KindlyMD's services through their insurance plans. Tim Pickett, PA-C, founder and CEO, stated, "This is a major milestone for KindlyMD. Now, the scope of services we provide at our Company-branded clinics, including behavioral healthcare and medical interventions incorporating alternative medicine, are covered by and reimbursable by the largest insurance providers across the state." On June 10, KDLY announced a collaboration with Curaleaf Holdings, Inc., (OTCQX: CURLF) to expand patient education on medical cannabis in Utah. This partnership includes community care events throughout the summer, aiming to enhance patient understanding of holistic pain management. Pickett noted, "Our collaboration with Curaleaf will provide more patients with access to pain management treatment options and alternative therapies, including medical cannabis care in the state of Utah." Additionally, KindlyMD further strengthened its position by contracting with Blue Cross Blue Shield, increasing its statewide insurance coverage to nearly 80%. Pickett commented, "The addition of Blue Cross Blue Shield under Utah's leading insurance payors reflects our commitment to transforming healthcare and making a meaningful difference in people's lives." As the cannabis industry continues to gain momentum, KDLY stands out for its unique approach to integrating medical cannabis into comprehensive pain management and behavioral health plans. This strong foundation, coupled with the company’s expanding insurance coverage and successful partnerships, positions KindlyMD for potential growth. For investors looking to tap into the burgeoning cannabis market, KDLY presents a compelling opportunity. Tilray Brands, Inc. (NASDAQ: TLRY) is a global leader in medical cannabis, dedicated to improving patient lives through a diverse portfolio of brands including Tilray, Aphria, Broken Coast, Symbios, and Navcora. From its origins as a licensed producer in Canada, Tilray has expanded its operations to Europe, establishing GMP-certified production facilities in Portugal and Germany. Today, Tilray Medical is a major supplier of medical cannabis across 20 countries and five continents, serving patients, healthcare professionals, and governments. Recently, Tilray announced it will release its financial results for the fourth quarter and full fiscal year ended May 31, 2024, on July 29, 2024, at market close. Despite recent fluctuations in share price, Tilray remains a formidable player in the cannabis industry, demonstrating long-term strength through its expanding craft beer business. Acquiring brands from Anheuser-Busch in 2023, Tilray has doubled its alcohol sales, diversifying its revenue streams and enhancing its position in a competitive market. TLRY’s strategic investments include building a $250 million cash reserve to support future acquisitions and operational expansion. This move, while diluting shares, positions Tilray advantageously for growth in the evolving cannabis sector. The company holds the top market share in Canada and Germany and distributes medical cannabis globally. In its Q3 2024 report, TLRY reported revenue of $188.3 million, a 30% increase from the previous year, although it fell short of the $198.3 million analysts' expectations. The company significantly reduced its loss to $82.1 million from $1.2 billion a year ago. With notable hedge fund interest and a robust portfolio, TLRY is well-positioned to benefit from potential federal legalization of medical cannabis in the U.S. Irwin Simon, CEO, highlighted Tilray's readiness to capitalize on regulatory changes, particularly the potential rescheduling of cannabis to Schedule III, which would facilitate the sale of pharmaceutical-grade products in the U.S. Canopy Growth Corporation (NASDAQ: CGC) is a global leader in the cannabis industry, committed to enhancing lives through innovative products and a diverse brand portfolio. With notable brands like Doja, 7ACRES, Tweed, and Deep Space, as well as vaporizer technology from Storz & Bickel, Canopy Growth stands out for its dedication to premium and mainstream cannabis products. The company recently reported its financial results for the fourth quarter and fiscal year ended March 31, 2024. For Q4 FY2024, Canopy Growth achieved a 7% increase in net revenue year-over-year, or 16% excluding divested businesses. This growth was significantly driven by a 43% revenue increase from Storz & Bickel, reflecting strong sales of the new Venty portable vaporizer. The Canadian cannabis sector saw a 16% rise in medical cannabis revenue, contributing to a 4% increase in overall Canadian cannabis revenue. In fiscal year 2024, Canopy Growth made impressive strides in reducing costs. The total cost of goods sold (COGS) decreased by 45%, with Canadian cannabis COGS dropping 54% year-over-year. Consolidated gross margins improved to 27%, marking a significant 4,600 basis point increase from the previous year. Despite an operating loss of $229 million and an adjusted EBITDA loss of $59 million, Canopy Growth showed a 72% improvement in adjusted EBITDA loss compared to FY2023. The company's financial stability is also notable, with $203 million in cash, cash equivalents, and short-term investments as of March 31, 2024. Strengthening balance sheet actions have positioned Canopy with no material debt obligations until March 2026. David Klein, CEO of Canopy Growth, highlighted the company’s strong foundation for future growth, emphasizing its momentum in the global cannabis markets and its readiness to capitalize on regulatory advancements in Germany and the U.S. As Canopy Growth enters FY2025, its broad portfolio of impactful brands and expanding U.S. ecosystem set the stage for continued success. Aurora Cannabis Inc. (NASDAQ: ACB), headquartered in Edmonton, Alberta, is a leading global player in the cannabis industry, serving medical and recreational markets across Canada, Europe, Australia, and South America. The company has built a diverse portfolio of cannabis brands, including Aurora Drift, San Rafael '71, Daily Special, Tasty's, and Greybeard for adult use, and MedReleaf, CanniMed, Aurora, and Whistler Medical Marijuana Co. for medical purposes. Additionally, Aurora's international brands include Pedanios, Bidiol, IndiMed, and CraftPlant. Aurora's strategic focus on innovation and high-quality products has positioned it as a significant force in the global cannabis market. The company recently reported its financial results for the fiscal year 2024, highlighting substantial improvements and operational efficiency. For Q4 2024, Aurora Cannabis achieved a 5% year-over-year increase in total net revenue, reaching $67.4 million. The global medical cannabis sector drove this growth, with net revenue rising 20% to $45.6 million. The company's strong performance in medical cannabis was bolstered by the acquisition of MedReleaf Australia and increased sales in Poland and the UK. Aurora's record annual adjusted EBITDA of $12.8 million marks its sixth consecutive quarter of positive adjusted EBITDA, reflecting the company's effective cost management and revenue growth. Aurora ended the fiscal year with approximately $180 million in cash and is debt-free in its cannabis business. The company remains focused on achieving positive free cash flow by the end of 2024. According to CEO Miguel Martin, Aurora's leadership in the global medical cannabis market is distinguished by its ability to meet diverse patient needs worldwide, underscored by a significant increase in its quarterly adjusted gross margin to 66%. With a solid financial foundation and a robust global presence, Aurora Cannabis is well-positioned for continued growth and success in the evolving cannabis industry. Disclaimers: RazorPitch Inc. "RazorPitch" is not operated by a licensed broker, a dealer, or a registered investment adviser. This content is for informational purposes only and is not intended to be investment advice. The Private Securities Litigation Reform Act of 1995 provides investors a safe harbor in regard to forward-looking statements. Any statements that express or involve discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, goals, assumptions, or future events or performance are not statements of historical fact may be forward looking statements. Forward looking statements are based on expectations, estimates, and projections at the time the statements are made that involve a number of risks and uncertainties which could cause actual results or events to differ materially from those presently anticipated. Forward looking statements in this action may be identified through use of words such as projects, foresee, expects, will, anticipates, estimates, believes, understands, or that by statements indicating certain actions & quote; may, could, or might occur. Understand there is no guarantee past performance will be indicative of future results. Investing in micro-cap and growth securities is highly speculative and carries an extremely high degree of risk. It is possible that an investors investment may be lost or impaired due to the speculative nature of the companies profiled. RazorPitch has been retained and compensated by Cambridge Consulting to assist in the production and distribution of content related to KDLY. RazorPitch is responsible for the production and distribution of this content. It should be expressly understood that under no circumstances does any information published herein represent a recommendation to buy or sell a security. This content is for informational purposes only, you should not construe any such information or other material as legal, tax, investment, financial, or other advice. Nothing contained in this article constitutes a solicitation, recommendation, endorsement, or offer by RazorPitch or any third party service provider to buy or sell any securities or other financial instruments. All content in this article is information of a general nature and does not address the circumstances of any particular individual or entity. Nothing in this article constitutes professional and/or financial advice, nor does any information in the article constitute a comprehensive or complete statement of the matters discussed or the law relating thereto. RazorPitch is not a fiduciary by virtue of any persons use of or access to this content. Contact Details Mark McKelvie +1 585-301-7700 Company Website http://razorpitch.com

July 22, 2024 07:00 AM Eastern Daylight Time

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BestGrowthStocks.Com Issues Analysis on the Next Beneficiaries of the AI Revolution

SoundHound AI Inc.

NEW YORK, NY / NewsDirect / July 22nd, 2024 / Best Growth Stocks, a leading independent equity research and corporate access firm focused on finding and reporting on the best growth stocks utilizing exclusive ai-assisted research recently issued a comprehensive analysis of SoundHound AI, Inc. a pioneer in advanced voice-enabled AI and conversational intelligence technologies and a comprehensive analysis of the next beneficiaries of the AI revolution. SoundHound AI, Inc. (NASDAQ: SOUN) has garnered significant investor attention following multiple recent announcements that could prove to be significant catalysts for the AI company. Best Growth Stock's full report offers an analysis of SoundHound’s operations, potential upcoming catalysts, growth drivers, financials, share structure, chart, and more. Bonus content “The Next Beneficiaries of the AI Revolution” offers a comprehensive analysis of the next beneficiaries of the AI revolution, which ones stand to benefit near term, and stocks under $15/share to watch within each sector. Access this full analysis and bonus AI report with no obligation: https://bestgrowthstocks.com/soun-analysis/ Access this full analysis and bonus AI report with no obligation: https://bestgrowthstocks.com/soun-analysis/ About SoundHound AI SoundHound AI (Nasdaq: SOUN), a global leader in conversational intelligence, offers voice AI solutions that let businesses offer incredible conversational experiences to their customers. Built on proprietary technology, SoundHound’s voice AI delivers best-in-class speed and accuracy in numerous languages to product creators across automotive, TV, and IoT, and to customer service industries via groundbreaking AI-driven products like Smart Answering, Smart Ordering, and Dynamic Drive Thru, an AI-powered multimodal food ordering solution. Along with SoundHound Chat AI, a powerful voice assistant with integrated Generative AI, SoundHound powers millions of products and services, and processes billions of interactions each year for world class businesses. About Best Growth Stocks Best Growth Stocks is a leading independent equity research and corporate access firm focused on finding and reporting on the best growth stocks utilizing our exclusive ai-assisted research. BGS is also a financial news provider, focused on giving investors direct access to CEOs of promising, publicly-traded companies, and market experts. Our CEO interviews aim to answer the questions that rest on the minds of current and future shareholders. This is not to be construed as financial advice. Please consult with a licensed financial advisor before making any investment decisions. Media Contact Best Growth Stocks Senior Editor: Steve Macalbry Editor@BestGrowthStocks.com SOURCE: BestGrowthStocks.Com Contact Details Media Source LLC Steve Macalbry +1 989-274-7778 Editor@bestgrowthstocks.com

July 22, 2024 07:00 AM Eastern Daylight Time

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Tonix Pharmaceuticals Awarded potential 34 million dollar Contract with U.S. Department of Defence

Tonix Pharmaceuticals

Tonix Pharmaceuticals CEO Dr. Seth Lederman joined Steve Darling from Proactive to share exciting news about a significant achievement for the company. Tonix Pharmaceuticals has been awarded a potential contract worth up to $34 million over five years by the Defense Threat Reduction Agency (DTRA), an agency within the U.S. Department of Defense. This contract aims to develop small molecule broad-spectrum antiviral agents for the prevention or treatment of infections, thereby enhancing the medical readiness of military personnel in biological threat environments. Dr. Lederman explained that Tonix’s program will concentrate on the optimization and development of its TNX-4200 program. The goal is to develop an orally available CD45 antagonist with broad-spectrum efficacy against various viral families through extensive preclinical evaluation. The program is expected to establish essential physicochemical properties, pharmacokinetics, and safety attributes to support an Investigational New Drug (IND) submission, ultimately funding a first-in-human Phase 1 clinical study. The agreement with DTRA is a strategic move to address the DoD’s objective of protecting U.S. Joint Forces from potential biological weapon threats. The DoD announced in December 2022 that it aims to move beyond the traditional ‘one bug, one drug’ approach and is seeking broad-spectrum drugs, as predicting which viruses or how many may be deployed in a biological threat scenario is challenging. Dr. Lederman emphasized that the collaboration with DTRA underscores Tonix Pharmaceuticals' commitment to advancing medical readiness and protection for military personnel. By developing a broad-spectrum antiviral agent, Tonix aims to provide a versatile and robust solution to potential viral threats, enhancing the preparedness and resilience of the U.S. military in diverse and unpredictable biological threat environments. The TNX-4200 program’s focus on creating an effective, orally available antiviral agent highlights Tonix’s innovative approach to addressing complex medical challenges. The successful development of this broad-spectrum antiviral could significantly impact the way viral infections are managed in military and potentially civilian populations, offering a proactive measure against a wide array of viral threats. Tonix Pharmaceuticals continues to be at the forefront of medical innovation, dedicated to developing cutting-edge solutions that meet the evolving needs of the healthcare and defense sectors. The support from the DoD through this substantial contract is a testament to the potential and importance of Tonix’s TNX-4200 program in safeguarding the health and readiness of military personnel against biological threats. Contact Details Proactive Investors +1 604-688-8158 na-editorial@proactiveinvestors.com

July 19, 2024 12:48 PM Eastern Daylight Time

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Mainz BioMed Seeks FDA Breakthrough Device Designation for Advanced Colorectal Cancer Test

Mainz Biomed N.V.

Mainz BioMed CEO Guido Baechler joined Steve Darling from Proactive to announce the company has submitted an application to the U.S. Food and Drug Administration requesting Breakthrough Device Designation for its innovative non-invasive Next Generation colorectal cancer screening product. This product incorporates a novel portfolio of mRNA biomarkers. Achieving this designation could potentially expedite the approval process, significantly benefiting early cancer detection efforts. Baechler emphasized that the regulatory submission is backed by consistently strong results from the company's clinical studies, ColoFuture and eAArly Detect, as well as data from a comprehensive pooled study encompassing both the European and U.S. cohorts, which were presented at ASCO 2024. These studies have culminated in the final configuration of the Next Generation Test. This test integrates the Fecal Immunochemical Test with proprietary mRNA biomarkers and is enhanced by an advanced AI and machine learning algorithm. This integrated approach is set to be employed in the FDA premarket approval study. The Next Generation Test configuration was rigorously evaluated in a clinical setting involving 295 subjects from 21 specialized gastroenterology centers across the United States. The results underscored the exceptional efficacy of Mainz Biomed’s multimodal screening test, which allows for precise differentiation among colorectal cancer, advanced adenomas, non-advanced adenomas, and samples with no pathological findings. The FDA’s Breakthrough Devices Designation program is designed to accelerate the development, assessment, and review of medical devices and combination products that provide more effective treatment or diagnosis for life-threatening or irreversibly debilitating conditions. This designation for Mainz BioMed's colorectal cancer test could pave the way for quicker market access and wider availability of this critical diagnostic tool. Contact Details Proactive North America +1 604-688-8158 na-editorial@proactiveinvestors.com

July 19, 2024 12:38 PM Eastern Daylight Time

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ABVC BioPharma's CEO Discusses New Drug Development and AI Integration

ABVC BioPharma

After successfully completing Phase II clinical trials for their medication to treat Major Depressive Disorder, ABVC BioPharma Inc. and AiBtl BioPharma Inc. are now embarking on a groundbreaking clinical study focused on Depression in Cancer Patients. This new study will integrate AI-driven solutions to address the significant challenge of depression among cancer patients, a condition that often complicates treatment and adversely affects overall quality of life. Dr. Uttam Patil shared with Steve Darling from Proactive that the study aims to gain a deeper understanding of the prevalence and impact of depression in cancer patients. It will explore innovative therapeutic approaches by integrating real-time patient monitoring and enhanced patient analysis through an AI model. This advanced methodology is expected to increase the lead time for clinical trials, utilizing novel and sophisticated treatment protocols. The clinical study will be conducted at the renowned Cedars-Sinai Medical Center, involving cancer patients who experience depressive symptoms. By leveraging advanced AI technologies and employing cutting-edge diagnostic and therapeutic techniques, the study aims to monitor and treat depression in participants under meticulous medical supervision. Dr. Patil emphasized that the integration of AI-driven solutions in this clinical study represents a significant leap forward in the treatment of depression in cancer patients. The use of real-time patient monitoring and AI-based analysis is anticipated to provide valuable insights and improve patient outcomes, setting a new standard for clinical trials in this area. The collaboration between ABVC BioPharma and AiBtl BioPharma highlights their commitment to advancing healthcare through innovative solutions. This study is poised to make a substantial impact on the management of depression in cancer patients, offering hope for improved quality of life and better treatment outcomes. Through this pioneering study, ABVC BioPharma and AiBtl BioPharma are at the forefront of integrating technology with healthcare, paving the way for future advancements in the field. The companies are dedicated to utilizing AI to enhance patient care and accelerate the development of effective treatments for depression in cancer patients. Contact Details Proactive North America +1 604-688-8158 na-editorial@proactiveinvestors.com

July 18, 2024 10:31 AM Eastern Daylight Time

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